that is, it is necessary for a successful peptide to be able to diffuse through an
outer cell wall and then form aggregates of peptides according to the barrel-
stave model. The ability to diffuse and aggregate is described by two groups of
parameters: general molecular parameters and amphipathic descriptors. Gen-
eral molecular parameters include molecular weight, charge, size, and shape pa-
rameters. An example of an amphipathic parameter is the hydrophobic dipole
moment, a property analogous to the standard electrostatic dipole moment ...
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