
© 2014 Elsevier Ltd
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Gene transfer vectors (DNA vehicles) and their
incorporation into biomaterials for bone repair
T. WIRTH and S. YL Ä -HERTTUALA , University of Eastern
Finland, Finland
DOI: 10.1533/9780857098104.3.374
Abstract : Bone is a very dynamic organ, consisting of cortical and
trabecular tissue types, and functioning as a protective and supportive
framework for the body. Despite bone’s physiological capacity to
regenerate, bone repair is not always satisfactory. This review aims
to introduce the reader to gene therapy and its potential in bone
regenerative medicine. We will discuss gene transfer methods ...