
© 2014 Elsevier Ltd
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Stem cell technology for in vitro bone tissue
engineering
H. DECLERCQ and M. CORNELISSEN ,
Ghent University, Belgium
DOI : 10.1533/9780857098104.3.406
Abstract : This chapter will focus on stem cells and their application in
in vitro bone tissue engineering. The chapter rst describes the isolation,
culture and derivation of human mesenchymal stem cells (from bone
marrow, adipose tissue and human embryonic stem cells). In the second
part, tissue engineering strategies will be described. To develop tissue
engineered constructs, there has been a shift from the traditional top-down
approach towar ...