Biomaterials for Bone Regeneration

220 Biomaterials for Bone Regeneration

plasma-based techniques (such as plasma grafting and plasma polymeriza-

tion) are only rarely reported. However, cold plasma technology can greatly

enhance cell–material interactions. Also, a better comprehension of these

interactions is of crucial importance to provide important details on which

plasma approach is most suitable.

Up till today, the major part of research has been done on surface engi-

neering of 2D substrates, despite the speci c needs of tissue engineering for

3D porous scaffolds. Only few studies have been reported to test the use of

cold plasma technology for surface modi cation of the interior of 3D porous

scaffolds. It is our opinion that this unexplored  eld will become more impor ...