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Electromagnetic Fields in Biology and Medicine
book

Electromagnetic Fields in Biology and Medicine

by Marko S. Markov
March 2015
Intermediate to advanced
476 pages
22h 5m
English
CRC Press
Content preview from Electromagnetic Fields in Biology and Medicine
34 Electromagnetic Fields in Biology and Medicine
cause free Ca
2+
to increase above its normal and tightly regulated value of approximately 100nM
in mammalian cells (Konieczny et al., 2012). In terms of PEMF mechanism, CaM is of particular
interest because it is the rst responder to changes in cytosolic Ca
2+
and because of the many roles it
plays in cell signaling and gene regulation pathways once activated by bound Ca
2+
(Faas et al., 2011).
In an immediate response to stress or injury, activated CaM binds to its primary enzyme target
constitutive nitric oxide synthase (cNOS, neuronal [nNOS] and/or endothelial [eNOS]), which, in
turn, binds to and catalyzes L-arginine resulting in the release of the signaling molecule NO. As
a gaseous free ...
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Publisher Resources

ISBN: 9781482248500