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Effect of PEMF on LPS-Induced
Chronic Inammation in Mice
Juan Carlos Pena-Philippides, Sean Hagberg,
Edwin Nemoto, and Tamara Roitbak
11.1 INTRODUCTION
Low-intensity pulsed electromagnetic elds (PEMFs) have been found to produce a variety of ben-
ecial biological effects and have been successfully employed as adjunctive therapy for a variety
of clinical conditions (Shupak, 2003; Guo et al., 2012). In the United States, PEMF is cleared by
FDA for use in treating postoperative pain and edema and approved by the Centers for Medicare
and Medicaid Services (CMS) for treating chronic wounds. PEMF signals induce electrical elds
in tissue, generat ...