400 Electromagnetic Fields in Biology and Medicine
24.2.2 ElEctrocHEmotHErapy: in ViVo studiEs
Bleomycin and cisplatin were tested in ECT protocol on a number of animal models in vivo.
Extensive studies on different animal models with different tumors, either transplantable or spon-
taneous, were performed. Antitumor effectiveness of ECT was tested on tumors in mice, rats,
hamsters, and rabbits. Tumors treated by ECT were either subcutaneous, grew in the muscle,
brain, or liver, and were of different types, for example, sarcomas, carcinomas, glioma, or mel-
anoma.
50,54–58
The studies demonstrated that with drug doses that have minimal or no antitu-
mor effectiveness, high (up to 80%) complete responses (CRs) of the ECT-treated tumors were
obta ...