Electromagnetic Fields in Biology and Medicine

113Magnetic Field Inuences on the Microcirculation

There are a number of important dosimetry issues that could exhibit signicant effects on micro-

circulation. It has been shown that it is more appropriate to consider biological responses to SMF

through the hypothesis of intensity windows, instead of intensity-response dependence (Markov

et al., 2004). Furthermore, it has been reported that the gradient component of SMF might be

responsible for the physiological responses in vivo (Okano and Ohkubo, 2005a,b), because the in

vitro effects of gradient elds on action potential generation (Cavopol et al., 1995; McLean et al.,

1995) and myosin phosphorylation (Engström et al., 2002) have been found mostly in the absolute

eld gradient range o