November 2018
Intermediate to advanced
272 pages
6h 51m
Japanese
book
エレガントなSciPy ―Pythonによる科学技術計算
by Juan Nunez-Iglesias, Stéfan van der Walt, Harriet Dashnow, 山崎 邦子, 山崎 康宏
Content preview from エレガントなSciPy ―Pythonによる科学技術計算
Become an O’Reilly member and get unlimited access to this title plus top books and audiobooks from O’Reilly and nearly 200 top publishers, thousands of courses curated by job role, 150+ live events each month,
O’Reilly covers everything we've got, with content to help us build a world-class technology community, upgrade the capabilities and competencies of our teams, and improve overall team performance as well as their engagement.I wanted to learn C and C++, but it didn't click for me until I picked up an O'Reilly book. When I went on the O’Reilly platform, I was astonished to find all the books there, plus live events and sandboxes so you could play around with the technology.I’ve been on the O’Reilly platform for more than eight years. I use a couple of learning platforms, but I'm on O'Reilly more than anybody else. When you're there, you start learning. I'm never disappointed.I'm always learning. So when I got on to O'Reilly, I was like a kid in a candy store. There are playlists. There are answers. There's on-demand training. It's worth its weight in gold, in terms of what it allows me to do.
28
1 章 エレガントな NumPy：科学 Python の基礎
with plt.style.context('style/thinner.mplstyle'):
binned_boxplot(x=log_gene_lengths, y=mean_log_counts)
■
続いて、同じプロットに
RPKM
正規化を行ったものです。
log_counts = np.log(counts_rpkm + 1)
mean_log_counts = np.mean(log_counts, axis=1)
log_gene_lengths = np.log(gene_lengths)
with plt.style.context('style/thinner.mplstyle'):
binned_boxplot(x=log_gene_lengths, y=mean_log_counts)
■
平均の発現リード数が、かなり平坦になりましたね。約
3,000
塩基対より長い遺伝子では特に平
坦です（短い遺伝子は、まだ発現が少ないままです。短すぎて
RPKM
手法の統計検定力では不十
分なのかもしれません）。
RPKM
正規化は、異なる遺伝子間の発現プロファイルを比較するのに役立つ場合があります。
長い遺伝子のリード数が大きいことは確認済みですが、実際に発現量が高いとは限りません。そこ
で、短い遺伝子と長い遺伝子を選び、両者のリード数を
RPKM
正規化の前後で比較してみましょ
う。
gene_idxs = np.nonzero((gene_names ...
Become an O’Reilly member and get unlimited access to this title plus top books and audiobooks from O’Reilly and nearly 200 top publishers, thousands of courses curated by job role, 150+ live events each month,
and much more.
Read now
Unlock full access
More than 5,000 organizations count on O’Reilly
O’Reilly covers everything we've got, with content to help us build a world-class technology community, upgrade the capabilities and competencies of our teams, and improve overall team performance as well as their engagement.Julian F.
I wanted to learn C and C++, but it didn't click for me until I picked up an O'Reilly book. When I went on the O’Reilly platform, I was astonished to find all the books there, plus live events and sandboxes so you could play around with the technology.Addison B.
I’ve been on the O’Reilly platform for more than eight years. I use a couple of learning platforms, but I'm on O'Reilly more than anybody else. When you're there, you start learning. I'm never disappointed.Amir M.
I'm always learning. So when I got on to O'Reilly, I was like a kid in a candy store. There are playlists. There are answers. There's on-demand training. It's worth its weight in gold, in terms of what it allows me to do.