Specialty Optical Fibers Handbook

monitor multiple disease markers, including cellular infiltration and collagen

catabolism and, hence, differentiate diseased and healthy tissues. They showed

that connective tissue contains lower densities of DNA, protein, and lipids

compared to higher densities in epithelial tissue. Collagen-specific tissue map-

ping by IR microspectroscopy revealed much higher levels of collagen deposition

in the connective tissues compared to that in the epithelium. Thus, inflammatory

events such as cellular infiltration and collagen deposition and catabolism can be

identified by IR microspectroscopy.

Neurological complications during critical illness remain a