April 2016
Beginner to intermediate
1036 pages
33h 39m
English
book
Statistics and Data Analysis for Microarrays Using R and Bioconductor, 2nd Edition
by Sorin Draghici
Content preview from Statistics and Data Analysis for Microarrays Using R and Bioconductor, 2nd Edition
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590 Statistics and Data Analysis for Microarrays Using R and Bioconductor
Implicit cluster
Boundary
Cluster center
Data point
(mean of replicates)
FIGURE 18.15: The residual-based cluster confidence approach [155, 257].
Each gene is repres ented by a mean of some individual measurements. The
confidence that a given gene b elongs to a cluster is inversely proportio nal to the
number of times the gene falls into a different cluster during the bootstr apping
process. The gene shown in red remains in the red cluster 3 out of 4 times,
which translates into a co nfidence of 0.75. Image courtesy of BioDiscovery Inc.
Cluster analysis 591
gene expres sion value ...
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