April 2016
Beginner to intermediate
1036 pages
33h 39m
English
book
Statistics and Data Analysis for Microarrays Using R and Bioconductor, 2nd Edition
by Sorin Draghici
Content preview from Statistics and Data Analysis for Microarrays Using R and Bioconductor, 2nd Edition
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Microarrays 49
FIGURE 3.7: The Illumina Golden Gate assay. The GoldenGate assay is
based on the BeadArray technology: as say oligonucleotides, containing an ad-
dress sequenc e , hybridize to gDNA to identify the allele at a given loci. After
processing and amplification, the amplified product binds to a bead on the ar-
ray that contains a complementary address sequence. Dual-color fluorescence
dyes, specific to e ach ASO, indicate the g enotype of the SNP from the gDNA
fragment. Courtesy o f Illumina, Inc.
50 St at ist ics and Data Analysis for Microarr ...
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