
864 Statistics and Data Analysis for Microarrays Using R and Bioconductor
FIGURE 25.12: GO::TermFinder input interface. GO::TermFinder only al-
lows to q ue ry one GO category at a time. The web-based version at SGD does
not calc ulate p-value s.
bles 25.1 a nd 25.2. The criteria used in these tables are described in details in
the fo llowing.
25.3.1 The statistical model.
The ontological analysis ca n be performed with a number of statistical mod-
els, including hypergeometric [93], binomial, χ
2
(chi-squa re) [157], and Fisher’s
exact test [296]. These tests were disc ussed in details in Chapter 23 but will
be brie fly summarized here. The probability ...