April 2016
Beginner to intermediate
1036 pages
33h 39m
English
book
Statistics and Data Analysis for Microarrays Using R and Bioconductor, 2nd Edition
by Sorin Draghici
Content preview from Statistics and Data Analysis for Microarrays Using R and Bioconductor, 2nd Edition
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Pathway analysis 913
FIGURE 28.5: The adherens junction pathway. Although the same receptor
INSR is also present in this pathway in the same position as it was in the
insulin pathway, its role here is not as impor tant sinc e it is only one of many
tyrosine kinas e receptors. A lack of INSR will not completely shut down this
pathway, as it would the insulin pathway. No ne of the existing ORA or FCS
approaches is able to take such information into consideration since they all
consider the pathways just sets of genes, disregarding their topology.
914
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