Chapter 41Overview on Bioprocess Simulation

Shin Je Lee, Dae Shik Kim, Jong Min Lee and Chonghun Han

41.1 Introduction

Bioprocess simulations are increasingly important and gaining traction in the biotechnology industry to improve process development. Whereas extremely high complexity of biosystem has been a bottleneck for bioprocess design and simulation, recent advances in not only modeling and design strategies but also computational capabilities enable us to analyze, optimize, and operate bioprocesses in a more quantitative manner. This chapter presents an overview on procedures for effective bioprocess simulation.

Section 41.2 discusses rational modeling and design of bioprocess, which is the first step toward optimal operation of bioprocess. ...

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