
5.6.1 PHYSBE
PHYSBE is a benchmark simulation of the human circu latory system. It was first introduced by
John Mcleod in 1966 in an article titled ‘‘PHYSBE . . . a Physiological Simulation Benchmark
Experiment.’’ Over the years, it has appeared in numerous references involving modeling and
simulation. The underlying dynamics have been simulated using the popular continuous simulation
programs including Simulink.
The human circulatory system is represented by three main components: the lungs (pulmonary
circulation), heart (coronary circulation), and the rest of the body (syst emic circulation). Coronary
and systemic circulations were further divided ...