30 Cell and Material Interface
(75:25) nanobrous scaffold using a rotating collector disk for collection of aligned
electrospun nanobers. These aligned nanobers were explored to fabricate tubular
scaffolds that could be used for engineering blood vessels. Their results demonstrated
that the nano-sized bers mimic the dimensions of natural ECM, provide mechani-
cal properties comparable to human coronary artery, and form a well-dened archi-
tecture for smooth muscle cell adhesion and proliferation.
94–96
Aligned bers not only
offer structural integrity but also maintain vasoactivity as they provide the necessary
mechanical strength that is needed to sustain high pressure of the human circulatory
system. Xu etal.
96
studied the response of ...