35Scaffold Processing Technologies for Tailored Cell Interactions
alternative to surgical techniques for skeletal muscle regeneration. One such example
is the study conducted by Riboldi etal.
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The authors have explored the use of elec-
trospun microbers made from degradable polyester urethane (PEU) as scaffolds for
skeletal muscle tissue engineering. Based on their preliminary studies using primary
human satellite cells (biopsy from a 38-year-old female), C2C12 (murine myoblast
cell line), and L6 (rat myoblast cell line), their results indicated that the electrospun
microbers of PEU showed satisfactory mechanical properties and encouraging cel-
lular response in terms of adhesion and differentiation. Based on these studies, the
electrospun ...