September 2018
Intermediate to advanced
294 pages
11h 13m
English
Content preview from Cell and Material Interface
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114 Cell and Material Interface
Focal adhesion (FA)
Fibronectin
Cell
nucleus
(A)
LM
LP
Stress fiber
Extracellular matrix (ECM)
Focal complex (FX)
Actin
α-Actinin
Myosin II
(B)
Vinculin
Talin
Paxillin
Integrin dimer
Fibronectin
Cell membrane
Extracellular matrix (ECM)
Cell–cell interactions
Soluble ECM
Integr
ins
(C)
Static ECM
Cadherin molecules
(homophilic-interaction)
Cell-matrix
interactions
FIGURE 5.3 (A) Surface–protein interaction—binding of integrin complex with bronec-
tin. (From Hoffmann, M. and Schwarz, U.S., BMC Syst. Biol., 7, 2, 2013.) (B) Cell interac-
tion within microenvironment. (From Shekaran, A. and Garcia, A.J., J. Biomed. Mater.
Res. A, 96(1), 261, 20 ...
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