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Cell and Material Interface
book

Cell and Material Interface

by Nihal Engin Vrana
September 2018
Intermediate to advanced content levelIntermediate to advanced
294 pages
11h 13m
English
CRC Press
Content preview from Cell and Material Interface
84 Cell and Material Interface
Laminins, a major component of basement membrane, controls cell adhesion,
migration, and differentiation. They exert their effects mainly through integrins and
act as a mediator of the interaction between the ECM and the cells (Tucker and
Chiquet-Ehrismann 2009). Some of the interactions provide specic functions, for
example, laminin 1 induces differentiation in epithelial cells, whereas laminin 2 pro-
motes neurite outgrowth from neural cells. On the other hand, laminin 5 is involved
in cell adhesion and migration, although this function is dependent on the proteolytic
processing of laminins by matrix metalloproteinases (MMPs) or plasmin. Moreover,
vascular membrane represents laminin 5 and 10 both of which med ...
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Publisher Resources

ISBN: 9781482256130