Skip to Main Content
Cell and Material Interface
book

Cell and Material Interface

by Nihal Engin Vrana
September 2018
Intermediate to advanced content levelIntermediate to advanced
294 pages
11h 13m
English
CRC Press
Content preview from Cell and Material Interface
152 Cell and Material Interface
6.2.2 protEin immobilization at tHE cEll–scaFFold intErFacE
Polymeric scaffolds can be made more suitable for cell attachment and growth by
surface modication. Various peptide sequences derived from ECM molecules such
as vitronectin, laminin, collagen, and brinogen have also been used to mediate cell
attachment (LeBaron and Athanisou, 2000). Among these, laminin 332 (formerly
termed laminin 5) is of special interest for skin tissue engineering since it is the
major component of the basement membrane of skin, synthesized by keratinocytes
for attachment. Its interaction with integrins plays important roles in the adhesion,
proliferation, and migration of skin cells (Tsuruta et al., 2008). Recently, it was
Become an O’Reilly member and get unlimited access to this title plus top books and audiobooks from O’Reilly and nearly 200 top publishers, thousands of courses curated by job role, 150+ live events each month,
and much more.
Start your free trial

You might also like

Emerging Nanotechnologies for Manufacturing, 2nd Edition

Emerging Nanotechnologies for Manufacturing, 2nd Edition

Waqar Ahmed, Mark J Jackson

Publisher Resources

ISBN: 9781482256130