April 2016
Intermediate to advanced
324 pages
14h 53m
English
book
Semiconductor Device-Based Sensors for Gas, Chemical, and Biomedical Applications
by Fan Ren, Stephen J Pearton
Content preview from Semiconductor Device-Based Sensors for Gas, Chemical, and Biomedical Applications
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26 Semiconductor Device-Based Sensors for Gas, Chemical, and Biomedical Applications
© 2011 by Taylor & Francis Group, LLC
surface, the same chemical reactions may not take place in the cleft. The response of the sensor on
the specic reactions of the NG 108-15 cells is discussed in more detail in Section 1.6.
1.6 RECORDING OF EXTRACELLULAR SIGNAL
As explained in Section 1.4.7, DFP is a very strong inhibitor of AChE. The ligand-gated channel
opened after binding of ACh for about 10ms. In case of differences in the Na
+
concentrations inside
30
60
90
3
6
21
PMSF
Amiloride
DMEM, no cells
7.65 pH
7.80 pH
7.73 pH
8.20 pH
Not buffered
PMSF
DFP
90
15
DFP
(only not-
buffered) ...
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