Bioaffinity Sensors Based on MOS Field-Effect Transistors 245
© 2011 by Taylor & Francis Group, LLC
equivalent circuit to calculate the transfer function justied the computation involved, and the value
of C
CL
was not reported.
The same platform has been used to study cell binding [105] with more elements considered
in the equivalent circuit to account for the cell and its interfaces. The results showed that a simple
membrane model could ultimately describe a well-bound cell on the chip surface and give informa-
tion about the binding and adhesion.
The ultimate aim of this effort is to produce a simple device useable in the eld to perform
real-time measurements of the change in transfer function with portable electronic packages. For
DNA detect ...