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added to the surface. The abrupt current change due to the exposure of PSA in a buffer solution
could be stabilized after it diffused into the buffer solution. The ultimate detection limit appears to
be a few picogram per milliliter [41].
2.8.4 Kidney injury molecule detection
Problems such as acute kidney injury (AKI) or acute renal failure (ARF) are unfortunately still associated
with a high mortality rate [162–164]. An important biomarker for early detection of AKI is the urinary
antigen known as kidney injury molecule-1 or KIM- ...