Outline of the Book

The book begins with a review of statistical problems arising in pharmaceutical drug development (Chapter 1, "Statistics in Drug Development"). This introductory chapter is followed by thirteen chapters that deal with statistical approaches used in drug discovery experiments, animal toxicology studies and clinical trials. Since some of the chapters discuss methods that are relevant at multiple stages of drug development (e.g., nonparametric methods), the chapters in this book are not grouped by the development stage. Table helps the reader identify chapters that deal with a particular area in pharmaceutical statistics.

Table Chapter list
ChapterDrug discoveryAnimal toxicologyClinical trials
Chapter 2, "Modern Classification ...

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