Pharmaceutical Statistics Using SAS
by Ph. D. Alex Dmitrienko, Ph. D. Christy Chuang-Stein, Sr. Ralph B. D'Agostino
1.7. Summary
Statistics, as a discipline, has broadened its scope significantly over the past 20 years. Wherever there is a need for quantification, statistics has a role. The abilityto think in terms of variability, to separate signals from noises, to control sources ofbias and variation, and to optimize under given conditions, makes statisticians a valuable partner in the development of a new pharmaceutical and biological products.
Mining historical data to add to our cumulative knowledge is a low-cost and high-yield activity. Many companies realize the value of this activity and are actively pursueit. For example, Bristol-Myers Squibb (Pink Sheet, December 13, 2004) formed a discoverytoxicology group and retrospectively analyzed approximately ...
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