February 2007
Beginner to intermediate
464 pages
16h
English
In this chapter, pharmacokinetic terminology frequently encountered in clinical trial assessment of human pharmacokinetics was reviewed, and the collection, measurement, and statistical assessment of pharmacokinetic data obtained in Phase I and clinical pharmacology studies were described. REML models were used to examine the most common pharmacokinetic data of practical interest, and tests for assessing bioequivalence and dose linearity were developed and implemented using PROC MIXED.
Read now
Unlock full access