Pharmaceutical Statistics Using SAS
by Ph. D. Alex Dmitrienko, Ph. D. Christy Chuang-Stein, Sr. Ralph B. D'Agostino
14.9. Summary
Decision analysis is a general approach to decisions, based on problem structuring, quantifying and optimising. In principle, it can be applied to any decision. We have seen a number of examples from drug development, with emphasis on clinical programs and trials. The examples range from the design of a single trial (sample size, sequential design), over the question about optimal dose, to the design of a program and project prioritization. The list could of course be expanded. In particular, more examples could be taken from discovery and commercial perspectives. An attractive feature of decision analysis is that it often promotes cross-skill cooperation and is a useful tool to facilitate mutual understanding of each others' ideas. ...
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