February 2007
Beginner to intermediate
464 pages
16h
English
book
Pharmaceutical Statistics Using SAS
by Ph. D. Alex Dmitrienko, Ph. D. Christy Chuang-Stein, Sr. Ralph B. D'Agostino
Content preview from Pharmaceutical Statistics Using SAS
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10.2. Research Question 1: Does "QCA" Decrease Mortality in Children with Severe Malaria?
According to a report released in 2003 by the World Health Organization, malaria remains one of the world's foremost health problems, killing at least one million people annually, mostly children under five years old in sub-Saharan Africa. Lactic acidosis (toxic levels of lactic acid in the blood) is a frequent complication in severe malaria and is an incremental statistical predictor ("independent risk factor") of death. Moreover, a plausible biological rationale supports the hypothesis that lactic acidosis is a contributing cause of death.
Dr. Peter Stacpoole of the University of Florida has spent decades investigating the safety and efficacy of dichloroacetate ...
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