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Medicinal Chemistry, 2nd Edition by P. Yogeeswari, D. Sriram

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Chapter 7

Sedatives, Hypnotics, and Anxiolytic Agents

LEARNING OBJECTIVES
  • Define insomnia and various causes of insomnia

  • Define sedation and hypnotics

  • List the classes of sedatives and hypnotics

  • Categorize barbiturates based on the duration of action

  • Describe various benzodiapine classes of drugs useful as sedatives and hypnotics

  • Describe the discovery of barbiturates

  • Describe how barbiturates act on the CNS to deliver sedation and hypnosis

  • Describe the methods of preparation of all barbiturates

  • Describe the relationship between structure of barbiturates and their biological activity

  • Learn the discovery pathway of benzodiazepines

  • Define the mechanism behind the action of benzodiazepines as sedatives

  • Describe the utility of Friedel-Crafts ...

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