May 2010
Intermediate to advanced
712 pages
18h 30m
English
Content preview from Medicinal Chemistry, 2nd Edition
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Chapter 21
Oral Anticoagulants
LEARNING OBJECTIVES
Describe clotting of blood and its significance
Define anticoagulants and their utility
Classify anticoagulants based on the chemical structure
Discuss the mode of action of anticoagulants
Discuss the synthetic protocol of various anticoagulants
List some new anticoagulants
21.1 INTRODUCTION
The coagulation of blood is a complex process during which blood forms solid clots. It is an important part of haemostasis whereby a damaged blood vessel wall is covered by a fibrin clot to stop haemorrhage and aid repair of the damaged vessel. Disorders in coagulation can lead to increased haemorrhage and/or thrombosis and embolism.
Blood coagulation process requires coagulation factors, calcium ...
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