Chapter 27
Antitubercular Agents
LEARNING OBJECTIVES
Define tuberculosis, its causes, and the treatment options
Describe the chemistry, mode of action, and utility of first-line treatment option for tuberculosis
Brief the utility of fluoroquinolones as antituberculers
27.1 INTRODUCTION
Tuberculosis is the most prevalent infectious disease worldwide and a leading killer caused by a single infectious agent, i.e., Mycobacterium tuberculosis. According to a WHO report, M. tuberculosis currently infects over two billion people worldwide, with some 30 million new cases reported every year. This intracellular infection accounts for at least three million deaths annually. Common infection sites of tuberculosis are lungs (primary site), brain, ...
Get Medicinal Chemistry, 2nd Edition now with the O’Reilly learning platform.
O’Reilly members experience books, live events, courses curated by job role, and more from O’Reilly and nearly 200 top publishers.
