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Medicinal Chemistry, 2nd Edition by P. Yogeeswari, D. Sriram

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Chapter 12

Antipyretics and Non-Steroidal Anti-Inflammatory Drugs

LEARNING OBJECTIVES
  • Define pyrexia, inflammation, their causes and modes of treatment options

  • Classify analgesics and anti-inflammatory drugs

  • Define eicosanoids and their role in inflammation

  • Describe the mode of action and complications of anti-inflammatory agents

  • Describe the importance of structure on activity of important classes of anti-inflammatory agents

  • List the synthesis and utility of other miscellaneous classes of drugs

  • Describe some drugs useful for the treatment of gout

  • Define COX-2 inhibitors and their significance

  • List some newer drugs in the class of analgesics and anti-inflammatory agents

12.1 INTRODUCTION

Fever usually results from microbes such as bacteria ...

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