Chapter 8

Anti-Epileptic Drugs

LEARNING OBJECTIVES
  • Define epilepsy and the causes of the disorder

  • Categorize various forms of the disorder

  • Categorize the anticonvulsant drugs based on the chemical class

  • Learn the basic structural composition for a molecule to act as anticonvulsants

  • Define pharmacophore model and how it can be derived

  • Categorize anticonvulsants on the basis of treatment of different seizure types

  • Define GABA and the importance of developing its analogues

  • Describe some newer anticonvulsants

8.1 INTRODUCTION: EPILEPSY AND TYPES OF SEIZURES

Epilepsy is a brain disorder in which clusters of nerve cells, or neurons, in the brain sometimes signal abnormally. In epilepsy, the normal pattern of neuronal activity becomes disturbed, ...

Get Medicinal Chemistry, 2nd Edition now with O’Reilly online learning.

O’Reilly members experience live online training, plus books, videos, and digital content from 200+ publishers.