April 2022
Beginner to intermediate
486 pages
10h 22m
Chinese
Content preview from 云端基因组学
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308
｜
第
10
章
如采用后一种方法，它应该放哪呢？云平台很多，每种云平台的运行时属性都要有
吗？
不，这些问题我们没有答案。我们就此打住，热一热爆米花，看开发者论战。如
要跟踪当前给定
Cromwell
后端能做什么，不能做什么，最好查看线上的后端文档
（
https://oreil.ly/7uTh6
）。现在，我们回头讨论在
GCP
平台上运行
Cromwell
的最
便捷和最易扩展的方法。
10.4
用
WDL Runner
封装
Cromwell
和
PAPI
的执行
只要你能运行
Cromwell
，能连因特网，你就可以从任何机器上通过
Cromwell
提交
工作流到
PAPI
执行，这一点值得重申。如前所述，我们之所以教你用
GCP
虚拟机，
是因为这种虚拟机只需少量设置，就能切入正题（运行大工作流），而且还能降低
那些目前不适合你的服务和设置所带来的风险。但你完全可以在自己笔记本电脑上
做相同事情，或者如果你觉得这样做有点不太靠谱，也可以用
AWS
或
Azure
虚拟机。
然而，用笔记本电脑的缺点是你需确保工作流运行全过程它在线（开机、联网）。
对于短时工作流，做到这一点可能没问题；但像全基因组分析这种全规模工作，你
需启动一个工作流，并保证机器通宵运转，不中断其执行。该场景再用笔记本电脑
就有难度。
WDL Runner
该出场了。该开源工具集稍稍封装
Cromwell
和
PAPI
。你只需输入
一条命令，
WDL Runner
就会在
GCP
平台创建一台虚拟机，启动一个容器，配置
Cromwell
，使其使用
PAPI
，并将工作流交
PAPI
执行，如图
10-6 ...
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O’Reilly covers everything we've got, with content to help us build a world-class technology community, upgrade the capabilities and competencies of our teams, and improve overall team performance as well as their engagement.Julian F.
I wanted to learn C and C++, but it didn't click for me until I picked up an O'Reilly book. When I went on the O’Reilly platform, I was astonished to find all the books there, plus live events and sandboxes so you could play around with the technology.Addison B.
I’ve been on the O’Reilly platform for more than eight years. I use a couple of learning platforms, but I'm on O'Reilly more than anybody else. When you're there, you start learning. I'm never disappointed.Amir M.
I'm always learning. So when I got on to O'Reilly, I was like a kid in a candy store. There are playlists. There are answers. There's on-demand training. It's worth its weight in gold, in terms of what it allows me to do.