April 2022
Beginner to intermediate
486 pages
10h 22m
Chinese
Content preview from 云端基因组学
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在
Terra
平台快捷运行多个工作流
｜
349
等规模的文件，如图
11-41
所示的
185 MB GVCF
文件（只用两美分？听着价格公道），
一般而言你最好用
GCP
平台控制台，当然用
gsutil
更好。但若需下载大文件（很多
GB
，需要花很多美元），你可能需要停下来仔细想想，拿不到该文件的本地副本，
你真的就做不了什么吗。例如，你计划在
IGV
浏览器查看
BAM
和
VCF
文件，以便
肉眼核查某些变异识别结果吗？请记住，你可以将
IGV
连到
GCS
。或者你想运行另
一种分析，但你还没有这样的一个工作流，或该分析要求交互处理吗？啊，那当然
可以……不过可以的话，你最好继续用云服务而不要使用本地环境。从原数据一直
到生成你可以用在论文中的图表，如果所有工作你都能在云上完成，不是很令人惊
喜吗？
这不是一个白日梦。如今已经可以这么做了，但你需要一些更好的工具而不只是虚
拟机，还需要一些不同于工作流的工具。你需要的是一个在云上进行交互分析的集
成开发环境，而
Terra
平台恰好也提供这种环境。
工作流生成的文件名使用直白的
.vcf
扩展名而非
.g.vcf
。虽然不是一定要
用
.g.vcf
，但我们建议用它，以表明文件实际上是一个
GVCF
而非常规
VCF
文件。这强调了一个事实，你不能单凭文件名和扩展名判断文件的内容和生
成方式。数据管理框架，如工作区数据模型，可以帮助我们跟踪数据之间的
关系，缓解这方面问题。
11.4
小结和下一步学习内容
包括本章在内的前四章，我们都一直在讲工作流。第
8
章，我们先从小的开始，学
习在单台虚拟机上运行预先编写好的
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O’Reilly covers everything we've got, with content to help us build a world-class technology community, upgrade the capabilities and competencies of our teams, and improve overall team performance as well as their engagement.Julian F.
I wanted to learn C and C++, but it didn't click for me until I picked up an O'Reilly book. When I went on the O’Reilly platform, I was astonished to find all the books there, plus live events and sandboxes so you could play around with the technology.Addison B.
I’ve been on the O’Reilly platform for more than eight years. I use a couple of learning platforms, but I'm on O'Reilly more than anybody else. When you're there, you start learning. I'm never disappointed.Amir M.
I'm always learning. So when I got on to O'Reilly, I was like a kid in a candy store. There are playlists. There are answers. There's on-demand training. It's worth its weight in gold, in terms of what it allows me to do.