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云端基因组学
book

云端基因组学

by Geraldine A. Van der Auwera, Brian D. O’Connor
April 2022
Beginner to intermediate
486 pages
10h 22m
Chinese
China Electric Power Press Ltd.
Content preview from 云端基因组学
393
13
Terra
平台自己组装工作区
在第
11
12
章,你学习了
Terra
平台工作流和交互式笔记本的用法。当时使用的工
作区已预先组装好。现在我们该学着组装自己的工作区,以便在
Terra
框架内完成
自己的分析工作。该领域提供大量备选方案和多种有效方法,故此我们不打算提供
一种万能路径,而是介绍三个应用场景。
场景一,我们从本书教程工作区(
https://oreil.ly/n7oOr
)的基本组件开始重新创建它,
阐明从头组建工作区的关键技巧。场景二、三,我们展示如何利用现有工作区,将
启动新项目必须要做的工作最小化。场景二,对于为特定分析而建成的工作区,例
如官方的
GATK
最佳实践工作区,我们将解释如何再往它里面添加数据。场景三,
我们将展示如何围绕从
Terra Data Library
导出的数据,构建分析工作流。我们深入
这三个场景之前,还是先探讨数据管理策略。三个场景都要用到该策略。
13.1
管理工作区内外数据
基因组分析上云,其中一项重要工作就是设计一种长期、可持续的数据管理策略,
特别是当你要处理大型数据集,而它们又是多种项目的输入。这个话题相当复杂,
我们在本书就不全面展开讨论。若要展开讲,那本书就不用讲别的了。但我们有必
要花点时间讨论几点关键注意事项。它们特别适用于
Terra
平台,而且会影响我们
的数据存放决策。
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Publisher Resources

ISBN: 9787519864422