April 2022
Beginner to intermediate
486 pages
10h 22m
Chinese
Content preview from 云端基因组学
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第
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-F CHROM -F POS -F QUAL \
-F BaseQRankSum -F MQRankSum -F ReadPosRankSum \
-F DP -F FS -F MQ -F QD -F SOR \
-F giab.callsets \
-GF GQ \
-O sandbox/motherSNP.giab.txt
VariantsToTable
命令应很快运行完，生成输出文件
motherSNP.giab.txt
。这是个纯
文本文件，因此我们可以用
cat
命令查看其部分内容：
In [41] ! cat sandbox/motherSNP.giab.txt | head -n300
查看前
300
行，我们会发现
VariantsToTable
工具生成一张表。表的每一行表示来自
VCF
文件的一条变异记录，表的每一列表示我们在导出命令指定的一个注释。如所
请求注释不存在（如纯合位点无
RankSum
注释，因为杂合位点才计算这种注释），
则该注释值用
NA
替代。拿到这个纯文本表格，我们可轻松加载整个变异识别结果集
及其注释值到
R
的一个
DataFrame
中。
为了将表格内容导入
R DataFrame
，我们调用
readr
库，并使用其
read_delim
函数，
加载
motherSNP.giab.txt
表到
motherSNP.giab DataFrame
对象。请注意
R
命令前的
%%R
符号，如前所述，该命令告知笔记本内核，该单元格所有代码按 ...
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I wanted to learn C and C++, but it didn't click for me until I picked up an O'Reilly book. When I went on the O’Reilly platform, I was astonished to find all the books there, plus live events and sandboxes so you could play around with the technology.Addison B.
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I'm always learning. So when I got on to O'Reilly, I was like a kid in a candy store. There are playlists. There are answers. There's on-demand training. It's worth its weight in gold, in terms of what it allows me to do.