April 2022
Beginner to intermediate
486 pages
10h 22m
Chinese
Content preview from 云端基因组学
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O’Reilly covers everything we've got, with content to help us build a world-class technology community, upgrade the capabilities and competencies of our teams, and improve overall team performance as well as their engagement.I wanted to learn C and C++, but it didn't click for me until I picked up an O'Reilly book. When I went on the O’Reilly platform, I was astonished to find all the books there, plus live events and sandboxes so you could play around with the technology.I’ve been on the O’Reilly platform for more than eight years. I use a couple of learning platforms, but I'm on O'Reilly more than anybody else. When you're there, you start learning. I'm never disappointed.I'm always learning. So when I got on to O'Reilly, I was like a kid in a candy store. There are playlists. There are answers. There's on-demand training. It's worth its weight in gold, in terms of what it allows me to do.
392
｜
第
12
章
建议你试试
Hail
工具集（
https://hail.is
），它以
Python
为基础专注于遗传学，可扩
展性非常强。它实现了一系列变异质量控制函数以及其他多种功能。与其他一些新
近开发的
GATK
工具一样，
Hail
也能用
Spark
并行分析，并已用在
UK Biobank
（
https://
oreil.ly/mes1R
）等大型数据集上执行全基因组分析研究（
genome-wide analysis
studies
，
GWAS
）。
Terra Library
有几个工作区专门使用
Hail
，其中包含一些教程笔
记本和一个完整
GWAS
示例（
https://oreil.ly/Q-LJD
）。
12.6
小结和下一步学习内容
本章，你学习了如何用
Terra
平台
Jupyter
软件与你的数据交互。你先学习了云端笔
记本的基本用法，搭建计算环境，打开示例笔记本，运行代码单元格。掌握这些基
本技能之后，你练习三类交互分析方法：一是在嵌入式
IGV
浏览器可视化基因组数
据；二是运行
GATK
命令并排错；三是用
R
绘制变异上下文注释。
本章并非要提供一份你可以在该环境完成的所有工作的详尽清单；本章的介绍只是
其冰山一角。然而，你现在应该掌握足够的技术和工具，能够开始改造你的分析代码，
使其兼容
Terra
框架。第
13
章，我们将向你展示如何将组件组装为你自己的工作区。
这些组件有数据、工具和来源不一的代码。
Become an O’Reilly member and get unlimited access to this title plus top books and audiobooks from O’Reilly and nearly 200 top publishers, thousands of courses curated by job role, 150+ live events each month,
and much more.
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I wanted to learn C and C++, but it didn't click for me until I picked up an O'Reilly book. When I went on the O’Reilly platform, I was astonished to find all the books there, plus live events and sandboxes so you could play around with the technology.Addison B.
I’ve been on the O’Reilly platform for more than eight years. I use a couple of learning platforms, but I'm on O'Reilly more than anybody else. When you're there, you start learning. I'm never disappointed.Amir M.
I'm always learning. So when I got on to O'Reilly, I was like a kid in a candy store. There are playlists. There are answers. There's on-demand training. It's worth its weight in gold, in terms of what it allows me to do.