April 2022
Beginner to intermediate
486 pages
10h 22m
Chinese
Content preview from 云端基因组学
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Jupyter Notebooks
中的交互式分析
｜
385
你认为这种运行和考察
GATK
命令的方法如何？我们可以继续用该方式重做第
5
章
至第
7
章的练习，实际上在公共
Terra
平台工作区有几个类似的
GATK
教程笔记本，
GATK
团队在其颇受欢迎的一系列面向全球的工作坊用的就是这些笔记本。我们鼓
励你了解其内容，以做进一步研究。
鉴于本书特别是本章的写作目的，我们还是重点介绍基因组数据分析工作常用的
Jupyter
笔记本用法。此外我们还知道几个功能，也非常想分享给你。我们继续讲吧。
下一步该绘制变异数据。变异数据的很多方面，你可能都想以可视化方式探究，但
我们无法一一介绍，实际上我们只介绍变异上下文注释值分布的可视化方法。它有
助于我们理解变异过滤方法，第
5
章曾讨论过该方法。
12.5
可视化变异上下文注释数据
你也许还记得我们在第
5
章，为了理解变异上下文注释的分布是如何告知我们有关
变异识别结果质量的信息，我们曾介绍过一种方法，使用了来自
GiaB
真集的注释。
当时我们采用一种可视化方法作评估，用多种方法绘制变异上下文注释值图表（密
度图和散点图）。如无法回忆起或已忘记细节，请花几分钟回头通读那一节，刷新
记忆。当时我们重点讲解概念，仅给出主要步骤。因此我们这里趁机讲讲如何用这
些关键步骤复现图
5-8
～图
5-11
所示图表。
12.5.1
用
VariantsToTable
导出感兴趣的注释值
我们之前用
GiaB
真集信息注释
Mother WGS
样本，并分析该样本得到
SNP
识别结果。
该结果存放在
VCF
文件。上述包括构造子集和注释在内的整个过程的操作步骤，请 ...
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O’Reilly covers everything we've got, with content to help us build a world-class technology community, upgrade the capabilities and competencies of our teams, and improve overall team performance as well as their engagement.Julian F.
I wanted to learn C and C++, but it didn't click for me until I picked up an O'Reilly book. When I went on the O’Reilly platform, I was astonished to find all the books there, plus live events and sandboxes so you could play around with the technology.Addison B.
I’ve been on the O’Reilly platform for more than eight years. I use a couple of learning platforms, but I'm on O'Reilly more than anybody else. When you're there, you start learning. I'm never disappointed.Amir M.
I'm always learning. So when I got on to O'Reilly, I was like a kid in a candy store. There are playlists. There are answers. There's on-demand training. It's worth its weight in gold, in terms of what it allows me to do.