April 2022
Beginner to intermediate
486 pages
10h 22m
Chinese
Content preview from 云端基因组学
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436
｜
第
14
章
用
FAIR
框架来分析它。第
1
章曾简单提过，
FAIR
是一个首字母缩略词，它代表可
寻找（
findability
）、可访问（
accessibility
）、可互操作（
interoperability
）和可重
用（
reusability
）。
FAIR
框架根据这四个特征来评估研究资产和服务的开放性。其
基本思想很简单：一项资产只有满足这四个支柱性要求，才能被视为开放（同开放
科学中的“开放”）。例如，一项分析要称得上开放，仅仅其代码满足在技术上对
其他计算工具可重用和可操作这两个要求还远远不够；其他研究者必须也能找到代
码，并获得一个完整、可正常运行的副本。
FAIR
原则的最初发布，重点突出了它们
在科研数据管理方面的必要性，但实际工作表明它们也能应用于其他类型的资产或
数字研究对象，比如代码和工具。
该案例研究的重点是可复现。可复现的含义跟
FAIR
框架的可重用最相近，而
FAIR
框架的其他三个特征将体现在我们的各种实现决策中。当我们重温我们所选择采用
的方法论时，将回顾这个框架。本章总结部分，在我们讨论这项工作的最终成果时，
还将回到该框架。现在我们一起来看本章项目要复现的原始研究成果。
14.1.2
案例研究的原始研究成果和历史
原始研究由
Donna J. Page
博士和
Matthieu J. Miossec
博士等人完成，其目标是通
过分析多家研究中心从
829
个
case
样本和
1252
个
control
样本采集的外显子组测
序数据，识别与一种叫作非综合征型法洛四联症的先天性心脏病（
non-syndromic ...
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I wanted to learn C and C++, but it didn't click for me until I picked up an O'Reilly book. When I went on the O’Reilly platform, I was astonished to find all the books there, plus live events and sandboxes so you could play around with the technology.Addison B.
I’ve been on the O’Reilly platform for more than eight years. I use a couple of learning platforms, but I'm on O'Reilly more than anybody else. When you're there, you start learning. I'm never disappointed.Amir M.
I'm always learning. So when I got on to O'Reilly, I was like a kid in a candy store. There are playlists. There are answers. There's on-demand training. It's worth its weight in gold, in terms of what it allows me to do.