Emerging Nanotechnologies for Manufacturing, 2nd Edition

43516.6 Nanocoating of pharmaceutical dosage forms

Strydom etal. [66] developed nanocoated cellulose used in the manufacture of tab-

lets via direct compression. The research demonstrated that by coating cellulose

microbers with nanolayers of polyvinylpyrrolidone and poly(styrenesulfonate), the

compaction properties of cellulose were dramatically improved without retarding the

drug dissolution. Additional clear advantages were demonstrated, such as minimal

weight gain of less than 1% as well as greater control over the surface properties of

the bers.

Another novel example of how nanocoatings may be utilized can be found in self-

diagnosis of ...