is book is dedicated to Professor Britton Chance (1913–2010), a pioneer in biophotonics and
a highly respected leader since the inception of this rapidly developing eld of the biomedical
sciences. rough his passion for research and education, he enriched the lives of generations
of scientists. His legacy will live on through the numerous scientists who trained under his
mentorship. is book commemorates his relentless spirit of innovation and discovery.