Handbook of Biomedical Optics

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19.1 Introduction

In this chapter, we discuss the principles of diuse optical

tomography (DOT) imaging using continuous wave (CW) and

frequency domain (FD) measurement systems. Section 19.2

describes the instruments and imaging congurations com-

monly used for acquiring CW and FD data. e numerical

approaches to transforming the measured data into meaning-

ful images in tissue are also discussed in Section 19.2, and the

importance of resolving the spectral content of the reemitted

light to extract physiologically relevant parameters is described.

ese measurements can be used to reduce inaccuracies in the

nal image