Handbook of Biomedical Optics

604 Handbook of Biomedical Optics

a variety of imaging methods including reected light (e.g.,

Dickensheets and Kino 1996, Liang et al. 2001, Tearney et al.

2002), confocal uorescence (single-photon excitation) (e.g.,

Gmitro and Aziz 1993, Sabharwal et al. 1999, Laemmel et al.

2004), and multiphoton uorescence (e.g., Helmchen et al. 2001,

Lelek et al. 2007, Myaing et al. 2006). To access more spectral

information, multispectral confocal endomicroscopy has been

demonstrated (e.g., Jean et al. 2007, Rouse and Gmitro 2000),

and we have recently reported confocal FLIM endomicroscopy

(Kennedy et al. 2009), using the setup shown in Figure ...