Handbook of Biomedical Optics

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22.1 Introduction

is chapter summarizes emerging methods for small animal

optical molecular imaging and it is based on an adaptation of the

reviews of the subject in Deliolanis et al. (2011) and Ntziachristos

and Razansky (2010). In particular, it presents current progress

in high-performance uorescence visualization in vivo through

entire animal bodies and tissues. is is a eld of the imaging

sciences that is only currently maturing to robust methodologies

for accurate, high-resolution photonic tissue imaging due to the

use of hybrid approaches, such as the combination of anatomical

and molecular imaging approaches or the use of opto-acous ...