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8.1 Introduction
Optical spectroscopic techniques have shown promising results
in the detection of diseases on cellular scale. ey do not require
tissue removal, can be performed in vivo, rapidly interrogate
large tissue surfaces, and permit the diagnosis to be made in real
time. While uorescence and Raman spectroscopy are eective
in revealing the molecular properties of tissue, the technique
called light scattering spectroscopy (LSS) is capable of char-
acterizing the structural properties of tissue on a cellular and
subcellular scale. LSS connects the spectroscopic properties of
light elastically scattered by small particles ...