Handbook of Biomedical Optics

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16.1 Introduction

Over the last two decades, considerable advances have been

made toward modeling light propagation in tissue. ese

advances have been mainly driven by the development of opti-

cal tomographic imaging techniques, which rely on accurate

modeling of light-tissue interactions in biomedical tissue. ese

techniques employ near-infrared (NIR) light in the wavelength

range of 600–900 nm, to probe biological tissue and image

physiological functions (Gibson et al. 2005, Nissilä et al. 2005,

Gibson and Dehghani 2009). e propagation of light in the NIR

is governed by the spatial distribution of the tissue’s scatteri ...