July 2012
Intermediate to advanced
758 pages
17h 12m
English
Content preview from Pharmaceutical Analysis
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Chapter 3
Para Dimethyl Amino Benzaldehyde (PDAB) and Para Dimethyl Amino Cinnamaldehyde (PDAC)
INTRODUCTION
Certain amines condense with various aldehydes in strongly acidic media to give products that are oxidisable to give colour. Among many, the following aldehydes are widely used. They are p-dimethyl aminobenzaldehyde, vanillin, formaldehyde, benzaldehyde, salicyaldehyde, paraldehyde, p-acetyl aminobenzaldehyde, m- and p-nitrobenzaldehyde, etc.
The reaction with aromatic amines produces Schiff bases.
STRUCTURES
MECHANISM OF ACTION
The mechanism of aldehydes which condenses with the aromatic amines involves the condensation of the aldehydes ...