Pharmaceutical Analysis

Chapter 6

Analysis of Diuretics

INTRODUCTION

Diuretics are the agents which increase the rate of urination. These agents are the most important in the pharmaceutical field.

Examples:	Frusemide
Hydrochlorothalidone
Thiazides
Benzthalidone, etc.

ANALYTICAL METHODS FOR DIURETICS

Based on the importance of these drugs, they can be analysed by the following methods:

1. Spectrophotometric methods:
   1. UV method
   2. Calorimetric method
2. HPLC methods
3. Titrimetric methods

1. Spectrophotometric methods: These methods are based on the principle of absorption of the radiation within the range of visible or UV range.
   1. UV methods: Analysis of diuretics in UV method is done based on the principle of dissolving the drug in appropriate solvent followed ...