July 2012
Intermediate to advanced
758 pages
17h 12m
English
Content preview from Pharmaceutical Analysis
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Chapter 6
Analysis of Diuretics
INTRODUCTION
Diuretics are the agents which increase the rate of urination. These agents are the most important in the pharmaceutical field.
| Examples: | Frusemide |
| Hydrochlorothalidone | |
| Thiazides | |
| Benzthalidone, etc. |
ANALYTICAL METHODS FOR DIURETICS
Based on the importance of these drugs, they can be analysed by the following methods:
- Spectrophotometric methods:
- UV method
- Calorimetric method
- HPLC methods
- Titrimetric methods
- Spectrophotometric methods: These methods are based on the principle of absorption of the radiation within the range of visible or UV range.
- UV methods: Analysis of diuretics in UV method is done based on the principle of dissolving the drug in appropriate solvent followed ...